Immune System, Part 2: Crash Course Anatomy & Physiology #46

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In the penultimate episode of Crash Course Anatomy & Physiology, Hank explains your adaptive immune system. The adaptive immune system’s humoral response guards extracellular terrain against pathogens. Hank also explains B cells, antibodies, and how vaccines work.

Pssst… we made flashcards to help you review the content in this episode! Find them on the free Crash Course App!

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Chapters:
Introduction: Adaptive Immune Responses 00:00
How B Cells Identify Antigens 2:14
B Cells Become Effector Cells & Memory Cells 4:05
How Antibodies Fight Antigens 5:22
Active and Passive Humoral Immunity 6:03
How Vaccines Work 6:27
Review 8:30

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38 Comments

  1. Great video! Love the animation and the detailed info on PAMPs and DAMPs.
    I go into great detail with a medical doctor on the immune system as well. Check it out on my channel: FredricksonHealthSolutions

  2. About the Flu Vaccine, even though we need a new vaccine every year, it's not for ourselves. It's so we don't spread it to the imunocompromised who are ineligible for the vaccine.

  3. They conveniently left out telling us the difference between imunology (where you naturally come in contact, your I.S. builds antibodies to the antigens and now you have life lont immunity… VS. Vaccinated. Unnatural, by passes the micro-biome and never educates your immune system to give you life long immunity. (hence booster shot)

  4. This and the other Immune System videos are some of the best in the whole A & P series. Great explanations and animations to describe adaptive immune responses to specific germs on a systemic level. Thank you!

  5. re 1:00 Adaptive IR 'Never Forgets". I suspect this is a generalization: I understand tha not all AIRs are permanent, or perhaps just unreliable in that a minute (undocumented) change in the pathogen makes it unrecognizable.

  6. My mom watched these fringe videos about how viruses emerge from the body as messenger type cells and then turn into bacteria or something like that. The people she watches claim that the immune system is the reason we get sick and is responding only to cells that come from within the body (as if that makes any sense) I've been procrastinating on watching the videos she's watched. She has had no interest in microbiology or evolutionary theory until this coronavirus started spreading and she immediately started watching videos talking about the conspiracies associated with the virus because she's subscribed to David Icke, Joe Dispenza, and other alternative medicine channels. She's one of those people who believes frequencies are imperative to health, that crystals emit healing energy, conventional food is poisonous, and chakras exist. Needless to say, she's completely convinced of these claims by these few and far in between medical "experts" who also just happen to be aired on conspiracy theory channels, some of which believe that the Earth is flat.

    I am so frustrated mostly because she has the gall to angrily spread this misinformation around in a self-righteous way like she has all the answers when she has admitted to me that she hasn't before ever researched into biology or other sciences outside of her fringe sphere. She still doesn't know the basics of evolutionary theory, she can't name a single organelle (she probably doesn't know what that is, even though I know I've told her) within the body (except for maybe the mitochondria), and she thinks specific frequencies can cure (or harm) anything.

    I don't necessarily have the time to debunk the massive amount of misinformation she's watched. A lot of the videos I've asked her to send me are at least an hour long and it's hard to want to take them seriously, even though, as an aspiring researcher, I know I should. At least I should be able to know how to debunk things, thoroughly and precisely.

    I'm just venting for the most part. I feel like it would be such a waste of time, but I know that I will most likely learn a lot more about biology than I have in the past by doing research into many more documented experiments and trials than I previously have.

    What would you do, internet commenter? If you were in my situation, would you try and debunk these claims that my mother so vehemently spreads around like a virus in and of itself? Is it worth the time? (subjective, I know)

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