Hank introduces us to that wondrous molecule deoxyribonucleic acid – also known as DNA – and explains how it replicates itself in our cells.
References:
http://www.nature.com/nature/dna50/watsoncrick.pdf
http://publications.nigms.nih.gov/thenewgenetics/chapter1.html
http://rst.gsfc.nasa.gov/Sect20/A12.html
http://www.nature.com/scitable/topicpage/discovery-of-dna-structure-and-function-watson-397
http://www.uic.edu/classes/phys/phys461/phys450/ANJUM04/
http://www.buzzle.com/articles/dna-replication-steps.html
http://www.dnareplication.info/stepsofdnareplication.php
How much DNA?
http://www.sdsc.edu/ScienceWomen/franklin.html
http://www.fmi.ch/members/marilyn.vaccaro/ewww/dna.pioneer.excerpt.htm
http://www.strangescience.net/rfranklin.htm
1:41 link to Biological Molecules http://www.youtube.com/watch?v=H8WJ2KENlK0
Table of Contents:
1) Nucleic Acids 1:30
2) DNA
-A) Polymers 1:53
-B) Three Ingredients 2:12
-C) Base Pairs 3:45
-D) Base Sequences 4:13
3) Pop Quiz 5:07
4) RNA 5:36
-A) Three Differences from DNA 5:43
5) Biolography 6:16
6) Replication 8:49
-A) Helicase and Unzipping 9:22
-B) Leading Strand 9:38
-C) DNA Polymerase 10:08
-D) RNA Primase 10:24
-E) Lagging Strand 10:46
-F) Okazaki Fragments 11:07
-F) DNA Ligase 11:47
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
Want to find Crash Course elsewhere on the internet?
Facebook – http://www.facebook.com/YouTubeCrashCourse
Twitter – http://www.twitter.com/TheCrashCourse
Instagram – https://www.instagram.com/thecrashcourse/
CC Kids: http://www.youtube.com/crashcoursekids
source
We will take u above carry minati …
Support it and subscribe ..🆗👌👌
I failed the pop quiz like a pro. Numbers scare me.
When he’s actually just holding a short stubby string and talking to it, then actually adding the dna strand when editing the vid 😂😂
Im fairly certain that the DNA strands run in the 5' to 3' direction. Not the other way around. Then again I am watching this video to understand it better so who knows.
I like how procrastinating teenagers get more likes than helpful people trying to give us a table of contents?!?!?!?!
Oh my god the joke on helicase (TT)
my first thought is lets make a DNA bridge to the moon that people can walk on
Amidst Corona, department drops the bomb that exam will take place in 30 days. Oh boy…
What he explained so easily scared me when I read it from the book .
0:46: HOLY MOTHER OF OBI-WAN!!!!!!!!!!!
this guy has brought me though all my school years, i cannot thank him enough!!
Summary-
Dna- deoxyribonucleic acid, stretching them end to end they would reach the sun 600 times. They r a 6 billion letter code. Dna is made of small repeating units (polymers) called nucleotides. Link them together and u have a polynucleotide. A nucleotide is made of-
• A five carbon sugar molecule called deoxyribose
• A phosphate group
• One of 4 nitrogen bases- adenine, thymine go together and cytosine and guanine go together. G and C pairing is stronger
Structure of dna is double helix(a twisted ladder) its main support is the sugar and phosphate binding together to form 2 twin backbones. These run in opposite directions, O2 pointing up and O2 pointing down. The left hand chain is from 5 prime to 3 prime and the opposite on the right hand chain.
Rna- has only 1 sugar phosphate backbone
• so it is a single stranded molecule, sugar is ribose (one O2 more)not deoxyribose
• Has uracil instead of thymine
Replication- copying of cells, helicase is an enzyme that unwinds the hydrogen bonds of the nitrogen bases, the point where the splitting starts is the replication fork. Top strand- leading strand and bottom strand called lagging strand. These go in opposite directions such that making dna from leading strand is easier than for lagging strand.
Leading strand- rna polymerase, an enzyme adds matching nitrogen bases. Rna primase provides a primase which helps the enzyme to make a new dna strand.
Lagging strand- rna polymerase can only copy dna in 5 prime to 3 prime direction so the copying is done in segments and using many other dna polymerase eg dna ligase
these brothers really be out here doing God's work what would I do without them
hank: Hey. wanna make one. FBI realizing that kids actually watched this: FBI OPEN UP
Last minute ap bio studying👀
Thank you for the video! There is a mistake at 10:50–10:59. In the video it said that the lagging strand runs 3'–>5' but the lagging strand actually runs 5'–>3'.
You are a HERO 🙏🏼 thank you for helping me finally understand this for the AP Exam
It's crazy the amount of things your body autonomically controls, I can see sometimes why more ignorant people would think we are created by a higher being. The intrinsic intelligence inside every cell, something that isn't even sentient can create something that we as humans have still not mastered.
3:24 if it always goes from 3' to 5', then why is the left strand 5'–>3' ?
good luck on the science exam you have on monday, and your only studying cause you failed the maths one you had today, and dont want to repeat that
when you realize this guy predicted the "big brain" meme at 6:33
slow the playback speed down to 0.5 from beginning to 0:47……..you're welcome
teacher: assigns 9 papers due in 4 days
me: I'm only 15 I'm too young to dieeeeee
youtube: click on this video is you want to know about the structure of DNA
me: stares at it for about 60 seconds
me:*clicks on video and drinks coffee so I don't fall asleep for 3 days*
Stealing from someone else, but watch the beginning on 0.5 playback speed and tell me he doesnt sound drunk
Yaz hh brothers