ATP & Respiration: Crash Course Biology #7

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In which Hank does some push-ups for science and describes the “economy” of cellular respiration and the various processes whereby our bodies create energy in the form of ATP.

Special thanks go to Stafford Fitness (www.staffordfitness.net) for allowing us to shoot the gym scenes in their facilities.

This video uses sounds from Freesound.org

Table of Contents:
1) Cellular Respiration 01:00
2) Adenosine Triphosphate 01:29
3) Glycolysis 4:13
A) Pyruvate Molecules 5:00
B) Anaerobic Respiration/Fermentation 5:33
C) Aerobic Respiration 6:45
4) Krebs Cycle 7:06
A) Acetyl COA 7:38
B) Oxaloacetic Acid 8:21
C) Biolography: Hans Krebs 8:37
D) NAD/FAD 9:48
5) Electron Transport Chain 10:55
6) Check the Math 12:33

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37 Comments

  1. Need a reviewer for an essay I wrote for extra credit, is this all correct?

    Cells use ATP or Adenosine Triphosphate as their energy currency, but where does it come from? It is created through a process known as cellular respiration consisting of three parts, Glycolysis, the Krebs Cycle, and the electron transport chain. Inside the cell's cytoplasm a Glucose molecule is turned into two Pyruvates and two NADH molecules through a process called glycolysis. Each of those pyruvates are then turned into three NADH molecules and one FADH2 by the Krebs cycle. Next, The NADHs from the Krebs Cycle and Glycolysis along with the FADH2 molecules are deposited inside the Mitochondrial Matrix. There are a set of four Complexes along the inner membrane of the mitochondria that take two electrons from each NADH and each FADH2 and pump out a total of six hydrogen Ions into the Intermembrane space, the area between the inner and outer membranes of the mitochondria. This creates an electrochemical gradient, meaning that those Hydrogen Ions want to get back into the Mitochondrial Matrix. A fifth Complex Lets these hydrogen ions run back through, like water through a water wheel. It uses the energy generated by the movement of the hydrogen ions to put together ADT, or Adenosine Diphosphate with An extra phosphate creating Adenosine Triphosphate, or ATP. The NADHs and FADH2s from one glucose molecule create 34 ATP molecules, as well as two extras as a byproduct of the Krebs cycle and four as byproducts of glycolysis. Take away two because of the initial two ATP spent doing glycolysis and one Glucose Molecule can be turned into 38 ATPs

  2. I formerly worked assisting children with Special Needs in public classrooms. I provided one-to-one assistance to a student who was born with Mitochondria and hydrocephalus. Hydrocephalus does not necessarily cause any disabilities or developmental delays if caught and treated early. My daughter's father was born with hydrocephalus and is a very healthy, athletic 6'3" 44 year old. Mitochondria is a rare condition with little information known so much more unknown. My general understanding is the body is not able to store & metabolize protein. The few known information I've seen states mitochondria comes from the maternal side (I am not sure if they are referring to the condition, disease?) How is it determined that the disabling condition mitochondria (or the lack of mitochondria passed on to the child) comes from the mother? All healthy functional adults have mitochondria, without it we wouldn't be able to do basic daily functions like pick up our toothbrush and brush our teeth. A child's chromosome (DNA) comes from the half paternal and half maternal. How is it the insufficient/weak/mutated/excessive (I don't think excessive is a possible reason for mitochondria) mitochondria does not come from the paternal side and the condition is link with the maternal? Perhaps there's new findings I don't know about but can you please explain what mitochondria condition or is it a disease is? How mitochondria (is only) linked to be contributed from the maternal side?

  3. This is by far the worst and most confusing video of this series so far. It needs rewritten from scratch. The others are much better.

  4. Can someone help me?!

    If I have 12 NADH from glycolysis, what is the net ATP? and furthermore, how much ATP is produced from 22 NADH during the Krebs cycle?

    This is a question I struggled with in AP. If you solve it please explain how you got the answer.

  5. It's 2020 and my "Science for Teachers" instructor assigned this video and I am a happy nerdfighter for that! Will continue to use these videos in my class as a student and I'll use crash course kids when I have my own classroom one day! 😀

  6. I had a small doubt:
    the immediate source of energy for metabolic reactions in a living cell is ____(is it glucose or atp)

  7. Everyone's like: My exam is tomorrow I don't understand it OMG!
    And I'm watching this video just out of curiosity cause I like chemistry and stuff.

  8. THIS ALL SEEMS SO COOL. there's something I don't get though. When working out, do you not feel any pain from torn muscles? Because whenever I work out I always make sure I have a lot of Oxygen for my next set. This is gained by a 45 second period of decently fast deep breathing. Then after I'm done doing 4×8 90lbs dumbell bench presses, or 200 crunches, or skull crushers, etc.(which is all intense for me), I never feel sore even after 1hr and 30mins of just working out then breathing. The only time I ever feel any range of soreness is when I'm done doing cardio – in which I inevitably go through anerobic respiration because My lungs can't keep up. That's obviously because of Lactid Acid. So, why is it that I don't feel any soreness? Is it really because I always take the time to breathe so much?

  9. Why would the yeast in a bottle at room temperature with one teaspoon of sugar produce just as much carbon dioxide through cellular respiration than a heated bottle with no sugar in it?

  10. When you still don't understand any biology and you're bingeing all the crash course videos. AND YOU STILL DON't UNDERSTAND, so your friend tutors you, AND YOU STILL DON'T UNDERSTAND. So you're in your room crying and the AP is in 3 days

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